PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Clinical trials for PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8 explained in plain language.
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Could a malaria drug help fight tough skin cancer?
Disease control TerminatedThis study tested whether adding the drug hydroxychloroquine to the standard two-drug treatment (dabrafenib and trametinib) could better control advanced melanoma that has a specific genetic change (BRAF V600E/K). It aimed to see if the three-drug combo could delay cancer growth …
Matched conditions: PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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New drug combo tested for Tough-to-Treat advanced cancers
Disease control TerminatedThis early-phase study tested the safety and effectiveness of adding a new drug called plinabulin to a combination of radiation and immunotherapy. It was for patients with advanced cancers (like lung, bladder, and melanoma) that had continued to grow despite prior immunotherapy. …
Matched conditions: PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Doctors test engineered virus to attack deadly skin cancer
Disease control TerminatedThis early-phase study tested a genetically modified virus designed to kill melanoma cancer cells. The virus was injected directly into tumors and given intravenously to patients with advanced melanoma that had stopped responding to standard treatments. The main goals were to fin…
Matched conditions: PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Two-Pronged attack tested against brain tumors
Disease control TerminatedThis early-phase study tested a combination of two drugs, bintrafusp alfa and pimasertib, for patients with cancer that had spread to the brain (brain metastases). The goal was to find a safe dose and see if the combination could help control the brain tumors and help patients li…
Matched conditions: PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC