PANCREATITIS, ACUTE

This study compares two diabetes medications, pioglitazone and empagliflozin, to see which better controls blood sugar in people whose diabetes is caused by chronic or recurrent acute pancreatitis. About 40 adults aged 18-80 will take one of the drugs, and researchers will measur…

This study tests a special blood-filtering device (Efferon LPS) in 150 adults with severe acute pancreatitis. The device is used alongside standard care to remove harmful substances from the blood, with the goal of reducing organ failure and improving survival. Participants are r…

This study tests whether giving a short course of intravenous hydrocortisone, an anti-inflammatory drug, to adults with severe acute pancreatitis can reduce inflammation and improve recovery. About 86 participants in intensive care will receive either the drug or a placebo. The g…

This study tests whether giving extra fluids through a vein along with a standard anti-inflammatory medicine (indometacin) can better prevent pancreatitis after a procedure that uses shock waves to break up painful stones in the pancreas. About 1,250 adults with chronic pancreati…

This study looks at whether increasing the dose of varenicline or adding another medication (bupropion) helps people with recurrent acute or chronic pancreatitis quit smoking. All 45 participants start with standard-dose varenicline; those still smoking after 6 weeks are randomly…

This study observes 1000 adults in Slovakia and Czechia who undergo an ERCP procedure to see how often they develop pancreatitis afterward. Researchers will also check if hospitals are using recommended prevention steps. The goal is to understand real-world complication rates and…

This study watches 150 adults who had part of their pancreas removed to see if high blood enzyme levels (hyperamylasemia) can predict serious problems like pancreatitis. Researchers want to improve how doctors define and catch these complications early. Participants just give blo…

This study tracks 300 adults getting a pancreas biopsy to see how often pancreatitis occurs and what raises the risk. Researchers will check blood enzyme levels a day after the procedure and follow up by phone. The goal is to make biopsies safer by identifying key risk factors.