PANCREATIC DUCTAL ADENOCARCINOMA

This early-stage study tested a new drug called BI 765883, given alone or with chemotherapy, for people with advanced pancreatic cancer that had spread or returned after surgery. The goal was to find a safe dose and see if it could shrink tumors. The study was stopped early after…

This study tested a combination of two drugs, niraparib and dostarlimab, in adults with advanced solid tumors that either had DNA repair problems or were sensitive to platinum chemotherapy. The goal was to see how many patients' tumors shrank or disappeared. The trial was stopped…

This early-phase trial tested a new drug, DCC-3084, alone or with other treatments, in people with advanced solid tumors linked to MAPK pathway mutations (like certain lung, pancreatic, or skin cancers). The study aimed to find safe doses and check if tumors shrank. It was termin…

This study tested a drug called PF-08046052/SGN-EGFRd2 in people with advanced solid tumors that could not be removed or had spread. The goal was to find a safe dose and check for side effects. The trial was terminated early, so results are limited. It involved 68 participants wi…

This study looked at whether surgically removing small tumors in the liver or lungs from pancreatic cancer could help people live longer. Only 5 people joined before the trial was stopped early. Participants first received chemotherapy before surgery. The goal was to compare surv…

This study tested a drug called Promitil in people with ovarian or pancreatic cancer that has specific gene mutations (BRCA or HRD) and has stopped responding to first treatment. The goal was to see if the drug could slow cancer growth and be safe. The study was stopped early, so…

This early-phase study tested a new drug called 177Lu-FF58, which delivers radiation directly to cancer cells that have specific markers (integrins). The goal was to check safety, find the right dose, and see if it shrinks tumors in people with advanced pancreatic, stomach, or br…

This study tested a new radioactive imaging agent called [68Ga]-FF58 to see how well it could detect certain solid tumors, including glioblastoma, breast cancer that spread to the brain, gastroesophageal cancer, and pancreatic cancer. The study was early-phase and involved 14 adu…

This study aimed to see if the antidepressant escitalopram could reduce depression in people with localized pancreatic cancer who were receiving chemotherapy. Only 4 participants were enrolled before the study was stopped early. The approach was to compare escitalopram to a place…