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Experimental cancer drug trial halted early after 29 patients

NCT ID NCT06287463

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 28 times

Summary

This early-phase trial tested a new drug, DCC-3084, alone or with other treatments, in people with advanced solid tumors linked to MAPK pathway mutations (like certain lung, pancreatic, or skin cancers). The study aimed to find safe doses and check if tumors shrank. It was terminated early after enrolling 29 participants, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • NEXT Oncology

    San Antonio, Texas, 78229, United States

  • NEXT Oncology Virginia

    Fairfax, Virginia, 22031, United States

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14263, United States

  • SCRI Florida Cancer Specialists

    Orlando, Florida, 32827, United States

  • SCRI HealthONE

    Denver, Colorado, 80218, United States

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • University of California San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, 94158, United States

  • University of Southern California - Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

Conditions

Explore the condition pages connected to this study.