PANCREAS ADENOCARCINOMA

This study is testing whether giving two different chemotherapy regimens in sequence—first Gemcitabine-Abraxane, then mFOLFIRINOX—can better shrink pancreatic tumors that are difficult or impossible to remove with surgery. The goal is to see if this approach makes successful surg…

This international trial is testing a combination of three existing treatments to reduce serious complications after a major surgery to remove pancreatic tumors. The bundle includes two short-term medications and a surgical patch, all given around the time of surgery. The goal is…

This study tests whether alternating two different chemotherapy combinations before surgery can better shrink borderline pancreatic tumors. The goal is to make more tumors removable by surgery and reduce the chance of cancer returning. About 35 adults with borderline pancreatic c…

This study is for people with advanced cancer that started in the upper digestive tract (like the stomach, pancreas, or bile ducts) and has spread to only a few other places. After three months of chemotherapy, if a special blood test finds no cancer DNA, patients are randomly as…

This study is testing a new treatment plan for people with pancreatic cancer that can be removed by surgery. The goal is to see if giving strong chemotherapy and targeted radiation *before* the operation helps surgeons remove all the cancer cells more effectively. Researchers wil…

This study is testing whether genetic analysis of pancreatic tumors can predict how well patients respond to chemotherapy before surgery. Researchers will give 45 patients with non-metastatic pancreatic cancer a standard chemotherapy combination called FOLFIRINOX, then analyze tu…

This study aims to understand why most pancreatic cancer patients experience severe, life-threatening weight loss called cachexia. Researchers will collect genetic samples from 100 patients with advanced pancreatic cancer to look for DNA patterns linked to this condition. The goa…