OSTEOSARCOMA
Clinical trials for OSTEOSARCOMA explained in plain language.
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New hope for hard-to-treat bone cancer: drug duo tested
Disease control CompletedThis study tested a new drug called azenosertib (ZN-c3) combined with the chemotherapy gemcitabine in people aged 12 and older whose osteosarcoma (a type of bone cancer) had returned or stopped responding to treatment. The goal was to see if the combination is safe and can slow o…
Matched conditions: OSTEOSARCOMA
Phase: PHASE1 • Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc • Aim: Disease control
Last updated May 26, 2026 09:40 UTC
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New hope for young bone cancer patients: immunotherapy drug tested in relapse
Disease control CompletedThis study tested a drug called avelumab in 19 children and young adults (ages 12 to 49) whose osteosarcoma (a type of bone cancer) had returned or was not responding to standard treatments. The goal was to see if avelumab could shrink tumors or stop the cancer from growing for a…
Matched conditions: OSTEOSARCOMA
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 26, 2026 09:27 UTC
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Targeted chemo cocktail shows promise against bone cancer
Disease control CompletedThis study tested a new way to treat osteosarcoma, a type of bone cancer, by giving two drugs directly into the artery that feeds the tumor. Ten patients received this local treatment along with standard chemotherapy before surgery. The goal was to see if this approach was safe a…
Matched conditions: OSTEOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Shanghai 6th People's Hospital • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New drug combo shows promise for tough sarcomas in young people
Disease control CompletedThis study tested a combination of two chemotherapy drugs, nab-paclitaxel and gemcitabine, in 59 teenagers and young adults whose sarcoma (a type of bone or soft tissue cancer) had come back or was not responding to standard treatment. The main goals were to see if the drug combo…
Matched conditions: OSTEOSARCOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Could a Radiation-Free MRI replace scans for kids with cancer?
Knowledge-focused CompletedThis study looked at whether a special type of MRI (DW-MRI) that uses no radiation can work as well as standard scans for children with bone or soft-tissue sarcomas. About 98 children participated to see if this safer method could accurately detect tumors and show how well treatm…
Matched conditions: OSTEOSARCOMA
Phase: NA • Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 09:37 UTC
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AI mines 700 patient records to uncover sarcoma survival clues
Knowledge-focused CompletedThis study looked back at the electronic health records of 700 people diagnosed with osteosarcoma or Ewing's sarcoma between 2003 and 2012. Researchers used machine learning to find patterns in the data, focusing on how long patients survived. The goal was to learn more about the…
Matched conditions: OSTEOSARCOMA
Sponsor: University of Milano Bicocca • Aim: Knowledge-focused
Last updated May 26, 2026 09:35 UTC
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Bone cancer biobank aims to unlock genetic secrets
Knowledge-focused CompletedThis study created a registry and biobank for people with osteosarcoma, a rare bone cancer. Researchers collected genetic samples from 362 participants, including patients and their family members, to compare genes and learn more about the disease. The goal was to support future …
Matched conditions: OSTEOSARCOMA
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Tumor DNA test aims to find best treatment for kids with hard-to-treat cancers
Knowledge-focused CompletedThis study tested whether analyzing the genetic makeup of a child's tumor could help doctors choose better treatments. 186 children with cancers that had come back or were not responding to standard therapy took part. The goal was to see if this approach was practical and safe, n…
Matched conditions: OSTEOSARCOMA
Phase: NA • Sponsor: Giselle Sholler • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC