OSTEOGENESIS IMPERFECTA
Clinical trials for OSTEOGENESIS IMPERFECTA explained in plain language.
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New telescoping rod aims to strengthen fragile bones in kids
Disease control CompletedThis study observed how well a special telescoping metal rod works for children with osteogenesis imperfecta (brittle bone disease). The rod is placed inside the bone during surgery to help it heal and grow stronger. Researchers followed 14 children for a year after their surgery…
Matched conditions: OSTEOGENESIS IMPERFECTA
Sponsor: Orthofix s.r.l. • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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New drug combo aims to strengthen brittle bones and prevent fractures
Disease control CompletedThis study tested a new treatment approach for adults with osteogenesis imperfecta (OI), a genetic condition that causes brittle bones and frequent fractures. Researchers wanted to see if a two-year course of a bone-building drug (teriparatide) followed by a single infusion of a …
Matched conditions: OSTEOGENESIS IMPERFECTA
Phase: PHASE4 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Can custom exercise help kids with brittle bones walk farther and feel better?
Symptom relief CompletedThis study tested whether a safe, personalized exercise program could help children and teenagers with osteogenesis imperfecta (brittle bone disease). Thirty participants aged 6 to 18 followed a supervised, one-year training program designed to be safe for their condition. The ma…
Matched conditions: OSTEOGENESIS IMPERFECTA
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated Mar 20, 2026 14:47 UTC
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Scientists track Children's brittle bone disease to unlock genetic secrets
Knowledge-focused CompletedThis study aimed to understand how osteogenesis imperfecta (brittle bone disease) develops over time in children and how different genes affect the symptoms. Researchers followed 46 children under age 12 with certain types of the condition, conducting regular check-ups and tests …
Matched conditions: OSTEOGENESIS IMPERFECTA
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:43 UTC
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Scientists hunt for blood clues to explain why brittle bone disease varies so much
Knowledge-focused CompletedThis study aimed to understand why osteogenesis imperfecta (brittle bone disease) varies in severity from person to person. Researchers analyzed blood samples from 66 adults with different forms of the disease to look for tiny molecules called microRNAs that might be linked to ho…
Matched conditions: OSTEOGENESIS IMPERFECTA
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists track brittle bone disease from birth to adulthood
Knowledge-focused CompletedThis study aimed to understand how a rare genetic condition called osteogenesis imperfecta (brittle bone disease) progresses over time in children and young adults. Researchers followed 88 participants from birth up to age 25 to observe how the disease affects walking, growth, bo…
Matched conditions: OSTEOGENESIS IMPERFECTA
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Doctors seek patients to unravel mysteries of brittle bone diseases
Knowledge-focused CompletedThis study aimed to better understand bone-related connective tissue disorders like osteogenesis imperfecta (brittle bone disease). It enrolled 180 people with suspected conditions and their family members for evaluation using standard tests like exams, X-rays, and blood draws. T…
Matched conditions: OSTEOGENESIS IMPERFECTA
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC