OSTEOARTHRITIS (OA)

This study tests a 2-hour online class called Empowered Relief for 100 adults with advanced osteoarthritis who cannot have joint replacement surgery. The class teaches simple pain management skills based on cognitive behavioral therapy and mindfulness. Researchers will measure pa…

This study will compare two types of total knee replacement surgery for people with knee osteoarthritis: one using a robotic device (VELYS) and the other done by hand. About 346 participants will be randomly assigned to one of the two methods. The goal is to see if the robotic ap…

This early-phase trial tests whether a shot made from stem cell secretions and growth factors can safely reduce pain and improve knee function in people with mild knee osteoarthritis. About 25 adults aged 30 to 55 with early-stage arthritis will receive the injection and be monit…

This study looks at whether a long-acting painkiller (bupivacaine-meloxicam) can reduce pain and the need for opioid painkillers after robot-assisted total knee replacement. About 150 adults aged 18 to 89 with knee osteoarthritis will take part. Researchers will measure pain leve…

This study looks at whether older adults (75+) with low muscle mass and strength before hip replacement surgery recover more slowly. About 20 volunteers will have their muscle health measured before surgery and be followed for 6 months after. The goal is to learn if pre-surgery m…