Osteoarthritis (OA)
Clinical trials for Osteoarthritis (OA) explained in plain language.
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New painkiller could cut opioid use after knee surgery
Symptom relief Not yet recruitingThis study tests whether a long-acting painkiller (bupivacaine-meloxicam) can reduce pain and the need for opioid medications after robot-assisted knee replacement. 150 adults with knee osteoarthritis will receive either the new painkiller or a standard injection. Researchers wil…
Matched conditions: OSTEOARTHRITIS (OA)
Phase 4 • Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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Can a single online class ease severe arthritis pain?
Symptom relief Not yet recruitingThis study tests a 2-hour online class called Empowered Relief for 100 adults with advanced knee or hip osteoarthritis who cannot have joint replacement surgery. The class teaches simple pain management skills based on cognitive behavioral therapy and mindfulness. Researchers wil…
Matched conditions: OSTEOARTHRITIS (OA)
Sponsor: Cedars-Sinai Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Could a fluid from stem cells ease knee pain without surgery?
Symptom relief Not yet recruitingThis early-phase trial tests whether injecting a fluid made from stem cells (called secretome) mixed with growth factors from the patient's own blood can safely reduce knee pain and improve function in people with mild knee osteoarthritis. The study will enroll 25 adults aged 30-…
Matched conditions: OSTEOARTHRITIS (OA)
Early phase 1 • Sponsor: University of the Punjab • Aim: Symptom relief
Last updated Jun 26, 2026 13:45 UTC