Orthopedic surgery
Clinical trials for Orthopedic surgery explained in plain language.
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Which works better for bone infections: cleaning or replacing hardware?
Disease control CompletedThis study compares two ways to treat early infections that happen after bone fracture surgery: cleaning the area and keeping the original hardware (DAIR) versus removing and replacing the hardware. Researchers will track 75 patients to see which method leads to better infection-…
Matched conditions: ORTHOPEDIC SURGERY
Sponsor: Antalya Health Sciences University • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Sleep hormone melatonin tested to stop Post-Surgery confusion in seniors
Prevention CompletedThis study tested whether giving melatonin, a natural sleep hormone, could prevent delirium (sudden confusion) in elderly patients after leg fracture surgery. Delirium affects up to 40% of older adults after major surgery and can lead to longer hospital stays and loss of independ…
Matched conditions: ORTHOPEDIC SURGERY
Phase 3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated Jun 26, 2026 14:38 UTC
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Can a VR goggle tour of the operating room calm nerves before surgery?
Symptom relief CompletedThis trial tests whether a virtual reality (VR) tour of the operating room can lower anxiety and fear in adults scheduled for arthroscopic orthopedic surgery. Participants in the intervention group watch a 9-minute 360-degree VR video that shows the journey from the ward to the o…
Matched conditions: ORTHOPEDIC SURGERY
Sponsor: Acibadem University • Aim: Symptom relief
Last updated Aug 21, 2026 00:00 UTC
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New program eases depression and anxiety in seniors facing hip or knee replacement
Symptom relief CompletedThis study tested a program that combines counseling (behavioral activation) with medication adjustments to reduce depression and anxiety in adults aged 60 and older who were scheduled for hip or knee replacement surgery. 116 participants were randomly assigned to receive the pro…
Matched conditions: ORTHOPEDIC SURGERY
Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Can a simple massage get knee replacement patients moving faster?
Symptom relief CompletedThis study tested whether adding manual lymphatic drainage massage to standard physiotherapy helps people recover knee movement faster after knee replacement surgery. Researchers measured joint range, swelling, and pain in 44 patients during their first week in the hospital. The …
Matched conditions: ORTHOPEDIC SURGERY
Sponsor: University Hospital, Limoges • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Which painkiller works better after bone surgery?
Symptom relief CompletedThis study compared two common pain medicines, pregabalin and gabapentin, given before surgery to 142 adults having leg or hip operations under spinal anesthesia. The goal was to see which one provided better pain control and longer relief after the procedure. Results showed whic…
Matched conditions: ORTHOPEDIC SURGERY
Sponsor: Muhammad Aamir Latif • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC