Which painkiller works better after bone surgery?
NCT ID NCT07389551
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two common pain medicines, pregabalin and gabapentin, given before surgery to 142 adults having leg or hip operations under spinal anesthesia. The goal was to see which one provided better pain control and longer relief after the procedure. Results showed which drug worked best for reducing pain and delaying the need for extra painkillers.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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142 people
The number who actually took part.
- Started
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Jul 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Either gender * Aged 20-60 years * Undergoing lower limb orthopedic surgeries under spinal anesthesia Exclusion Criteria: * Patients with a previous history of spine interventions, including surgery or injections (transforaminal, epidural, or facetal) for pain relief * Patients under any sort of pain modulation therapy, like transcutaneous electrical nerve stimulation * Patients had a long-term history of any analgesia use * Those with psychiatric disorders, alcohol/drug dependence, hepatic, renal, cardiac, or pulmonary abnormalities, * With a history of allergies to gabapentinoids
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Victoria Hospital/Qaid-e-Azam Medical College
Bahawalpur, Punjab Province, 63100, Pakistan
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