ORAL CANCER

This study tests a three-drug combination (carboplatin, nab-paclitaxel, and durvalumab) given before surgery to people with advanced head and neck cancer that can be removed. The goal is to shrink or kill the cancer so that radiation (which has harsh side effects) may not be need…

This study tests whether the immunotherapy drug pembrolizumab (Keytruda) combined with radiation works better than the standard chemotherapy drug cisplatin with radiation for patients with a certain type of head and neck cancer (p16-positive). About 126 adults with advanced or in…

This study tests an online program called Empowered Survivor, designed to help people who have had oral or throat cancer feel more confident managing their health after treatment. Researchers are comparing it to a free online tool already available for cancer survivors. The goal …

This study looks at whether a smartphone app can help people recover shoulder and neck function after oral cancer surgery that removed lymph nodes. About 80 patients will either get standard rehab instructions or use an app with daily exercise reminders and video check-ins with a…

This study compares two pain management strategies for adults with oral cancer who have moderate to severe pain. One group receives the opioid tramadol, while the other gets a combination of pregabalin and naproxen sodium. Over 7 days, researchers measure pain reduction, side eff…

This pilot study tests whether strawberry gummies can promote oral health in 36 adults, including smokers and non-smokers. Participants eat 8 gummies a day for 7 days, and researchers measure inflammation markers in saliva and urine. The goal is to see how the body absorbs strawb…

This study tests whether sharing real-life experiences of people affected by cancer can motivate more adults in rural India to get screened for oral, breast, and cervical cancers. About 1,120 men and women aged 30-59 who have not been screened recently will be randomly assigned t…