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New combo aims to skip radiation for head and neck cancer patients

NCT ID NCT03174275

First seen Feb 26, 2026 · Last updated May 24, 2026 · Updated 12 times

Summary

This study tests a combination of two chemotherapy drugs and an immunotherapy drug given before surgery to people with advanced head and neck cancer that can be removed. The goal is to shrink or kill the cancer enough so that patients may not need radiation after surgery, which can cause severe side effects. About 39 adults with stage III or IV squamous cell carcinoma of the head and neck are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Lineberger Comprehensive Cancer Center at University of North Carolina Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.