ORAL CANCER

This study tests a low-cost approach to treat pre-cancerous and cancerous mouth lesions using a drug (5-ALA) that makes abnormal cells sensitive to light, followed by laser light delivered through a handheld device. The goal is to destroy these lesions without surgery. The trial …

This study tests whether rinsing with hydrogen water can reduce inflammation, mouth sores, and pain in people recovering from oral cancer surgery with free flap reconstruction. Thirty-six participants will use either hydrogen water or regular water for oral care over 7 days. Rese…

This study tests whether an AI-powered physiotherapy system is safe, usable, and helpful for oral cancer patients who have trouble opening their mouth or moving their neck and shoulders after treatment. Fifteen participants will use the system for 4 to 6 weeks, doing daily exerci…

This study tests whether a mobile app with swallowing exercises can help people with oral cancer recover better after reconstructive surgery. About 72 adults in Taiwan will either get standard care or standard care plus the app. Researchers will measure swallowing function, anxie…

This study explores whether using mixed reality (like advanced 3D goggles) can help surgeons better plan and perform oral cancer removal and tissue rebuilding. Thirty adults with oral cancer will be randomly assigned to one of three groups: surgery with mixed reality, surgery wit…

This study will test whether using a special index that predicts low blood pressure can help doctors manage blood pressure better during oral cancer surgery. About 100 adults having elective oral cancer surgery with flap reconstruction will take part. The goal is to see if this a…

This study looks at how the upper trapezius muscle changes in oral cancer patients who have had neck surgery and have shoulder blade movement problems. Researchers will use ultrasound to measure muscle size and thickness, and check how well patients can lift their arms. The goal …