Older adults (65 years and older)

This study tests a new approach called GHOSTLY+ to help older adults (65+) maintain muscle strength while hospitalized. The system combines light leg exercises with a blood flow restriction cuff and a tablet game that responds to muscle activity. 120 patients across three hospita…

This trial tests a 12-week home-based digital cardiac rehabilitation program for people with coronary artery disease. It aims to improve heart health, reduce hospital visits, and enhance quality of life, especially for older adults, women, and those with other health issues. The …

This study is testing whether taking a daily zinc supplement for one year can help older adults (65+) avoid infections, reduce antibiotic use, and spend more time at home instead of in the hospital. Researchers will compare 8,000 participants who take zinc to those who do not, tr…

This study tests whether breathing a special mix of low and high oxygen air (called intermittent hypoxic-hyperoxic training) can help lower blood sugar in people with type 2 diabetes. About 250 adults aged 50-74 will be split into groups receiving either a 3-day or 10-day course …

This study tests whether a coordinated care program called I-CONNECT can improve the health and well-being of older adults (65+) who have depression or bipolar disorder and at least two chronic physical conditions like diabetes or high blood pressure. Participants receive persona…

This study tests whether using a virtual reality (VR) headset can make behavioral activation therapy more effective for older adults (65+) with major depression. Thirty participants will use VR to engage in activities that boost mood, and researchers will measure changes in depre…

This study explores whether a short virtual reality (VR) tour of Bali can reduce loneliness in adults aged 65 and older. Participants are randomly assigned to either a 13-minute VR travel experience or a puzzle activity, and their feelings of loneliness are measured before and af…

This pilot study tests a program called SONATA that helps older adults (65+) with advanced cancer strengthen their social connections. The program includes goal-setting, mapping out one's support network, and improving communication with loved ones. Researchers want to see if the…

This study tests a care transition program called OSCAR-S for adults aged 65 and older who are having planned colorectal surgery. The program provides extra support from a nurse coach to help patients and families manage recovery at home after leaving the hospital. The goal is to…

This study is testing whether adding breathing exercises to balance training can improve thinking skills in people aged 65 and older. Forty participants will do 30 minutes of balance exercises plus 15 minutes of breathing exercises twice a week for 8 weeks. Researchers will measu…

This study tests whether cognitive behavioral therapy for insomnia (CBT-I) can help older African Americans sleep better and think more clearly. Twenty participants will receive 8 weekly sleep training sessions via Zoom or a single education session. Researchers will measure slee…

This study tests whether a 12-week digital exercise program, with or without personal coaching, can help adults aged 65 and older become more physically active after total hip replacement. Participants will be randomly assigned to one of three groups: the digital program with coa…

This study tests whether sending nostalgic, personal messages and asking people to track their steps can encourage older adults (ages 65-74) to walk more. Over 14 days, 1,000 participants will receive daily messages through a mobile app. Some will also track their steps. The goal…

This study looks at how different levels of fatigue during power training affect strength, muscle function, and recovery in healthy adults aged 65 to 85. Participants will do three supervised leg-press sessions, stopping when their movement speed drops by 10% or 30%, or matching …

This study looks at how physical activity and thinking skills change as people age, focusing on Hispanic and non-Hispanic adults aged 55-85. Researchers want to see if it's possible to enroll 100 volunteers and gather early data on aging patterns. The goal is to better understand…

This study looks at what helps older adults (65+) understand how climate change affects their health. Researchers will ask 159 participants to fill out surveys about their thinking skills, physical activity, and climate change knowledge. The goal is to find ways to better teach s…