NEUROFIBROMATOSIS 1
Clinical trials for NEUROFIBROMATOSIS 1 explained in plain language.
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New gel shows promise for shrinking painful skin tumors in rare genetic condition
Disease control CompletedThis study tested a gel called NFX-179 on skin tumors (cutaneous neurofibromas) in 199 adults with neurofibromatosis type 1. Participants applied the gel daily for 6 months to up to 10 tumors. The goal was to see if the gel safely shrinks the tumors. Results showed some tumors re…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE2 • Sponsor: NFlection Therapeutics, Inc. • Aim: Disease control
Last updated May 18, 2026 11:59 UTC
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Video therapy boosts Well-Being in neurofibromatosis patients
Symptom relief CompletedThis study tested two stress and symptom management programs delivered through live video for adults with neurofibromatosis (NF1, NF2, or schwannomatosis). The goal was to see if these programs could improve physical and mental quality of life. 228 participants who reported diffi…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 26, 2026 12:05 UTC
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Could a common supplement help kids with NF1 think and move better?
Symptom relief CompletedThis study tested whether N-acetylcysteine (NAC), an over-the-counter antioxidant, could improve learning, behavior, and motor skills in children with neurofibromatosis type 1 (NF1). Five children aged 8–16 took part in a double-blind, placebo-controlled trial. The goal was to se…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Symptom relief
Last updated May 26, 2026 12:02 UTC
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Chill out: skin cooling may ease pain of NF1 procedures
Symptom relief CompletedThis early-phase study tested whether cooling the skin before and during laser or injection treatments for neurofibromatosis type 1 (NF1) skin bumps can reduce pain. Thirteen adults with NF1 each received treatment on one cooled site and one non-cooled site. The main goal was to …
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Massive gene hunt for NF1 skin tumors completed
Knowledge-focused CompletedThis study collected genetic samples from over 1,000 adults with Neurofibromatosis Type 1 (NF1) to find which gene variations are linked to the development of skin tumors called cutaneous neurofibromas. By analyzing DNA, researchers hope to better understand why symptoms vary so …
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC