NEUROFIBROMATOSIS 1
Clinical trials for NEUROFIBROMATOSIS 1 explained in plain language.
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Kitchen spice and olive oil tested as potential tumor treatment
Disease control OngoingThis early-stage study is testing whether daily doses of curcumin (from turmeric) and a special high-phenolic olive oil are safe and might help reduce skin tumors in adults with Neurofibromatosis Type 1 (NF1). The 23 participants take these supplements twice daily for up to a yea…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Global trial tests drug to shrink debilitating tumors
Disease control OngoingThis global Phase 3 study is testing whether the drug selumetinib is effective and safe for adults with neurofibromatosis type 1 (NF1) who have painful, inoperable tumors called plexiform neurofibromas. The main goal is to see if the drug can shrink these tumors and reduce chroni…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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First chinese trial tests drug for rare genetic nerve tumors
Disease control OngoingThis early-phase study is testing the safety and effects of the drug selumetinib in Chinese children and adults with Neurofibromatosis Type 1 (NF1) who have inoperable nerve tumors called plexiform neurofibromas. About 32 participants will take the oral medication twice daily unt…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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New hope for kids with untreatable tumors
Disease control OngoingThis study tested an oral drug called selumetinib in children and young adults with neurofibromatosis type 1 (NF1) who have plexiform neurofibromas—nerve tumors that cannot be safely removed by surgery. The goal was to see if the drug could shrink these tumors or stop them from g…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Could a common cosmetic drug shrink painful skin tumors?
Disease control ENROLLING_BY_INVITATIONThis early-stage study is testing whether giving monthly injections of an FDA-approved drug called Kybella (deoxycholate) can safely reduce the size and improve the appearance of skin tumors in adults with Neurofibromatosis Type 1. Researchers will treat up to 50 tumors in a sing…
Matched conditions: NEUROFIBROMATOSIS 1
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 09, 2026 14:27 UTC
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Hunting the clues: can scans predict deadly cancer in genetic disorder?
Knowledge-focused OngoingThis study aims to find better ways to predict which benign nerve tumors in people with Neurofibromatosis type 1 (NF1) might turn into a dangerous, hard-to-treat cancer called MPNST. Researchers will follow 80 participants considered at high risk, using annual whole-body MRI scan…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Mapping the mystery: 5-Year study tracks NF1 skin tumors with 3D cameras
Knowledge-focused OngoingThis study aims to understand how and why benign skin tumors grow in people with Neurofibromatosis Type 1 (NF1). Researchers at Johns Hopkins will follow 500 participants for five years, using annual 3D whole-body imaging to track changes in these tumors over time. The goal is to…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Blood test breakthrough could replace scans for NF1 tumor tracking
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to find signals in the blood that can tell doctors about tumor growth in people with Neurofibromatosis type 1 (NF1). Researchers will study 200 people with NF1, using blood tests and full-body MRI scans to see if specific blood markers match the size and number of…
Matched conditions: NEUROFIBROMATOSIS 1
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC