NEURODEGENERATIVE DISEASE
Clinical trials for NEURODEGENERATIVE DISEASE explained in plain language.
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One-shot gene therapy aims to stop rare nerve disease in its tracks
Disease control Recruiting nowThis study tests a single dose of a gene therapy called NTLA-2001 in 60 people with a rare inherited nerve disease (ATTRv-PN). The goal is to see if it can safely reduce harmful protein buildup and slow nerve damage compared to a placebo. Participants must have a confirmed diagno…
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: PHASE3 • Sponsor: Intellia Therapeutics • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New PET tracer could sharpen Alzheimer's diagnosis
Diagnosis Recruiting nowThis study tests a new imaging tracer called [18F]NIDF that binds to tau tangles in the brain, which are linked to Alzheimer's and other neurodegenerative diseases. About 20 healthy volunteers and patients will receive the tracer and undergo PET scans to see how well it works and…
Matched conditions: NEURODEGENERATIVE DISEASE
Sponsor: Tianjin Medical University • Aim: Diagnosis
Last updated May 26, 2026 03:16 UTC
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Mindfulness classes aim to ease emotional toll of Parkinson's on patients and families
Symptom relief Recruiting nowThis study tests whether eight weeks of mindfulness training can improve emotional well-being and strengthen the relationship between people with Parkinson's disease and their family caregivers. About 200 Chinese patient-caregiver pairs will be randomly assigned to either the min…
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated May 26, 2026 03:09 UTC
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Walking meditation may help brain disease patients build resilience
Symptom relief Recruiting nowThis study tests a walking meditation program called iWalk for adults with neurodegenerative diseases like multiple sclerosis. The goal is to see if it helps improve resilience, thinking, and well-being. About 90 participants will be randomly assigned to the program or a control …
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: NA • Sponsor: University of Illinois at Urbana-Champaign • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Wine's secret power: tiny cell particles may hold key to healthy aging
Knowledge-focused Recruiting nowThis study looks at how one serving of red or white wine changes tiny particles called extracellular vesicles in the blood of healthy adults aged 35 to 65. These particles help cells talk to each other and may affect heart and brain health. Researchers will compare blood samples …
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: NA • Sponsor: University of Seville • Aim: Knowledge-focused
Last updated May 26, 2026 03:23 UTC
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NIH launches massive screening study for brain disorders
Knowledge-focused Recruiting nowThis study screens up to 5,000 healthy volunteers and people at risk for conditions like autism or other brain disorders. The goal is to evaluate participants through interviews and cognitive tests to see if they qualify for other research studies at NIH. It does not offer treatm…
Matched conditions: NEURODEGENERATIVE DISEASE
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated May 26, 2026 03:21 UTC
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Brain scans reveal hidden protein clues in dementia
Knowledge-focused Recruiting nowThis study uses a special brain scan called PET to measure a protein called tau, which builds up in people with brain cell damage. Researchers want to see how tau buildup relates to memory, thinking, and brain changes over time. About 300 adults with conditions like Alzheimer's, …
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: PHASE2, PHASE3 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 26, 2026 03:17 UTC
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Sniffing out Parkinson's: new study hunts for early warning signs in nose, blood, and urine
Knowledge-focused Recruiting nowThis study aims to find early biological markers for Parkinson's disease, multiple system atrophy, and Lewy body dementia by analyzing samples from the nose, blood, and urine. Researchers will combine clinical exams, brain scans, and advanced lab tests to build a model that can t…
Matched conditions: NEURODEGENERATIVE DISEASE
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC