NEURODEGENERATIVE DISEASE
Clinical trials for NEURODEGENERATIVE DISEASE explained in plain language.
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Gene-Editing shot aims to halt rare nerve disease in phase 3 trial
Disease control Recruiting nowThis study tests a single dose of NTLA-2001, a gene-editing therapy, in 60 adults with hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN), a genetic disease that damages nerves. The goal is to see if the treatment can stop or slow the disease by lowering a harmfu…
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: PHASE3 • Sponsor: Intellia Therapeutics • Aim: Disease control
Last updated May 06, 2026 16:02 UTC
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New PET tracer could spot Alzheimer's tau tangles earlier
Diagnosis Recruiting nowThis study tests a new radioactive tracer called [18F]NIDF for PET brain scans. The tracer binds to tau tangles, which are linked to Alzheimer's and other brain diseases. Researchers want to see if it is safe and can accurately show where tau builds up in the brain. About 20 heal…
Matched conditions: NEURODEGENERATIVE DISEASE
Sponsor: Tianjin Medical University • Aim: Diagnosis
Last updated May 13, 2026 16:00 UTC
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Can walking meditation boost resilience in brain disease?
Symptom relief Recruiting nowThis study tests a walking meditation program called iWalk for adults with neurodegenerative diseases like multiple sclerosis. The goal is to see if it helps improve resilience, thinking skills, and overall well-being. Researchers will enroll 90 participants to check if the progr…
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: NA • Sponsor: University of Illinois at Urbana-Champaign • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Mindfulness for two: new study aims to ease Parkinson's stress on patients and caregivers
Symptom relief Recruiting nowThis study tests whether an 8-week mindfulness program for people with Parkinson's disease and their family caregivers can reduce negative emotions and improve their relationship. About 200 Chinese patient-caregiver pairs will either take the mindfulness classes or continue usual…
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Wine study uncovers secrets of healthy aging at cellular level
Knowledge-focused Recruiting nowThis study looks at how one serving of red or white wine changes tiny particles called extracellular vesicles in the blood. These particles help cells talk to each other and may influence heart and brain health. Researchers will compare blood samples from 8 healthy adults before …
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: NA • Sponsor: University of Seville • Aim: Knowledge-focused
Last updated May 17, 2026 01:18 UTC
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Sniffing out Parkinson's: new study hunts for early warning signs in nose, blood, and urine
Knowledge-focused Recruiting nowThis study aims to find early biological markers for Parkinson's disease and similar brain disorders by analyzing samples from the nose, blood, and urine. Researchers will compare results from 180 people—including those with Parkinson's, multiple system atrophy, Lewy body dementi…
Matched conditions: NEURODEGENERATIVE DISEASE
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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New brain scan study aims to uncover secrets of memory loss diseases
Knowledge-focused Recruiting nowThis study uses a special brain scan called PET to measure a protein called tau, which builds up in people with brain cell damage. Researchers will look at 300 adults with diseases like Alzheimer's, frontotemporal degeneration, and Parkinson's to see how tau buildup relates to me…
Matched conditions: NEURODEGENERATIVE DISEASE
Phase: PHASE2, PHASE3 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Massive NIH screening study seeks 5,000 volunteers to unlock brain disorder secrets
Knowledge-focused Recruiting nowThis study screens up to 5,000 people, including healthy volunteers and those at risk for conditions like autism or psychiatric disorders. The goal is to evaluate participants through interviews, cognitive tests, and other assessments to better understand these conditions. It doe…
Matched conditions: NEURODEGENERATIVE DISEASE
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated May 11, 2026 20:41 UTC