NASOPHARYNGEAL CARCINOMA

This study looked at whether adding chemotherapy to modern radiation therapy (IMRT) is necessary for people with intermediate-risk nasopharyngeal cancer. 338 patients were randomly assigned to receive either radiation alone or radiation plus the chemotherapy drug cisplatin. The g…

This study tested a new combination of chemotherapy drugs (nab-paclitaxel, cisplatin, and fluorouracil) followed by standard chemoradiation in 60 people with advanced nasopharyngeal cancer, a type of throat cancer common in southern China. The goal was to see if the new drug comb…

This study tested a combination of two drugs, TQB2618 and penpulimab, in 47 people with advanced nasopharyngeal carcinoma that had come back or spread. Some participants had already tried standard treatments, while others were new to therapy. The goal was to see if the combo coul…

This early-phase trial tested a new treatment for people with advanced nasopharyngeal cancer that is linked to the Epstein-Barr virus. The treatment uses specially engineered immune cells (TCR-T cells) that can recognize and attack the virus on cancer cells, plus they release a c…

This study tested whether adding the immunotherapy drug nivolumab to standard chemoradiation helps patients with stage II to IVB nasopharyngeal cancer. Forty adults with this type of throat cancer took part. The main goal was to see if patients could complete all planned treatmen…

This study tested an experimental drug called KL-A167 in 153 adults whose nasopharyngeal cancer had returned or spread after standard treatments. The goal was to see if the drug could shrink tumors. The trial is now complete, and results will show how well the drug works and how …

This study tested whether adding the immunotherapy drug pembrolizumab after standard chemoradiation helps control advanced nasopharyngeal cancer. 53 patients received up to 17 cycles of pembrolizumab over about a year. The main goal was to see how many patients remained cancer-fr…

This study tested a new way to find small cancer spots in neck lymph nodes of people with nasopharyngeal cancer. It combined MRI scans with a special ultrasound that uses a contrast agent. The goal was to create better rules for diagnosis and see how accurate they are. 348 patien…

This study looked at whether measuring certain proteins in the blood (pre-albumin, retinol-binding protein, and transferrin) can help find malnutrition early in people with advanced nasopharyngeal cancer who are getting chemotherapy and radiation. The study included 60 adults age…