MYELODYSPLASTIC SYNDROMES
Clinical trials for MYELODYSPLASTIC SYNDROMES explained in plain language.
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New combo therapy aims to tame High-Risk bone marrow cancer
Disease control Not yet recruitingThis early-phase trial tests a new two-drug combination (pacritinib plus azacitidine) in 25 people with moderate to very high risk myelodysplastic syndrome (MDS), a bone marrow disorder. The first part finds the safest dose; the second part checks how well the combination works a…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE1, PHASE2 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated May 26, 2026 05:56 UTC
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New drug aims to free MDS patients from blood transfusions
Disease control Not yet recruitingThis study tests an experimental drug called TAK-226 in 27 Japanese adults with a bone marrow condition called myelodysplastic syndromes (MDS) who need regular blood transfusions. The goal is to see if TAK-226 can help them go without transfusions for at least 8 weeks. Participan…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE2 • Sponsor: Takeda • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New hope: drug may stop leukemia relapse in High-Risk patients
Disease control Not yet recruitingThis study tests whether the drug interferon-α can help prevent acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) from coming back in patients with a TP53 gene mutation who have already had a stem cell transplant. About 100 people aged 12-65 will receive interferon-α…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE2 • Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Can blood cancer patients safely stop anti-rejection drugs sooner?
Disease control Not yet recruitingThis study tests whether patients who receive a stem cell transplant for blood cancers can safely stop the anti-rejection drug tacrolimus earlier than usual. The goal is to reduce side effects while still preventing graft-versus-host disease (GVHD). About 50 participants will be …
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: PHASE1 • Sponsor: Stanford University • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Can music and mindfulness ease the toll of stem cell transplants?
Symptom relief Not yet recruitingThis study aims to see if a special online program combining mindfulness and music therapy can help people feel better during stem cell transplant recovery. About 165 adults with blood cancers like leukemia or lymphoma will take part. The program is designed to improve quality of…
Matched conditions: MYELODYSPLASTIC SYNDROMES
Phase: NA • Sponsor: University of Miami • Aim: Symptom relief
Last updated May 26, 2026 05:47 UTC
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Massive study to uncover hidden links between immune Flare-Ups and blood cancers
Knowledge-focused Not yet recruitingThis study will follow 5,000 adults who have immune system problems (like inflammation or autoimmune disease) to see how often they also develop blood disorders, including a rare condition called VEXAS syndrome. Researchers will track new cases over time to better understand the …
Matched conditions: MYELODYSPLASTIC SYNDROMES
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 20, 2026 11:55 UTC