MUSCLE-INVASIVE BLADDER CARCINOMA
Clinical trials for MUSCLE-INVASIVE BLADDER CARCINOMA explained in plain language.
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Immunotherapy may let some bladder cancer patients keep their bladder
Disease control OngoingThis study tests whether the immunotherapy drug pembrolizumab can shrink muscle-invasive bladder cancer enough to avoid removing the bladder. About 46 adults with localized bladder cancer will receive pembrolizumab before standard treatments. Those whose cancer completely respond…
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: PHASE2 • Sponsor: Matthew Galsky • Aim: Disease control
Last updated May 26, 2026 05:25 UTC
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Bladder cancer drug combo trial halted before enrolling patients
Disease control TerminatedThis study was designed for people with muscle-invasive bladder cancer who cannot receive the standard chemotherapy drug cisplatin. It aimed to test whether the targeted therapy erdafitinib, alone or combined with the immunotherapy atezolizumab, could shrink tumors before surgery…
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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New hope for bladder cancer: chemo, immunotherapy, and radiation may save the bladder
Disease control OngoingThis study tests a treatment plan for muscle-invasive bladder cancer that aims to avoid bladder removal. About 71 participants will receive chemotherapy and an immunotherapy drug (toripalimab) before radiation therapy, plus more immunotherapy during radiation. The goal is to see …
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Immunotherapy boost may help bladder cancer patients avoid surgery
Disease control OngoingThis study tests whether adding the immunotherapy drug atezolizumab to standard chemoradiation helps people with muscle-invasive bladder cancer live longer without their cancer returning. About 475 adults with localized disease that hasn't spread are taking part. The goal is to s…
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 26, 2026 19:37 UTC
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New radiation technique aims to cut bladder cancer Treatment's Gut-Wrenching side effects
Symptom relief OngoingThis study tests a daily customized radiation therapy for muscle-invasive bladder cancer. The goal is to see if this approach reduces diarrhea and other bowel problems compared to standard radiation. About 110 adults with bladder cancer that hasn't spread widely are taking part.
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: NA • Sponsor: Varian, a Siemens Healthineers Company • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC