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Bladder cancer drug combo trial pulled before it even started

NCT ID NCT05564416

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 35 times

Summary

This trial was designed to test two drugs—erdafitinib and atezolizumab—for people with muscle invasive bladder cancer who cannot take the standard chemotherapy drug cisplatin. Erdafitinib targets a specific gene change that can drive cancer growth, while atezolizumab helps the immune system attack cancer cells. The study was withdrawn before any patients were enrolled, so no data were collected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

erdafitinib and atezolizumab

What this could lead to

If successful, this could point toward a new treatment option for bladder cancer patients who cannot receive standard chemotherapy.

What could go wrong

The trial was withdrawn before enrolling any participants, so no results are available. It is unclear if the approach would be effective or safe.

Conditions

The condition(s) this trial relates to.

infiltrating bladder urothelial carcinoma transitional cell carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.