Metastatic solid tumors
Clinical trials for Metastatic solid tumors explained in plain language.
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New drug combo targets Hard-to-Treat cancers
Disease control Stopped earlyThis early-phase study tests an experimental drug called INCB177054, given alone or with another drug (retifanlimab), in people with advanced or metastatic solid tumors that have not responded to standard treatments. The main goals are to check safety and find the right dose. Abo…
Matched conditions: METASTATIC SOLID TUMORS
Phase 1/2 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Experimental combo therapy for advanced cancer shows early promise but trial cut short
Disease control Stopped earlyThis early-stage trial tested a new drug (GEN1042) combined with radiation, with or without another immunotherapy (pembrolizumab), in people with metastatic solid tumors that had no standard treatment options. The goal was to see if the combination was safe and could shrink tumor…
Matched conditions: METASTATIC SOLID TUMORS
Phase 1/2 • Sponsor: Genmab • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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New pill targets common cancer mutation in early trial
Disease control Stopped earlyThis early-phase study tested a new drug called BGB-53038, which blocks a family of KRAS proteins that help some cancers grow. It was given alone or with other drugs to 47 people with advanced solid tumors (like lung, colon, or pancreatic cancer) that have KRAS mutations. The mai…
Matched conditions: METASTATIC SOLID TUMORS
Phase 1 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC