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Experimental combo therapy for metastatic cancer shows early promise but trial halted

NCT ID NCT05491317

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 29 times

Summary

This trial tested a new drug (GEN1042) combined with radiation, with or without another drug (pembrolizumab), in people with advanced solid tumors that had spread and no standard treatment options. The goal was to see if the combination was safe and could shrink tumors, including those not directly treated with radiation. The study was terminated early after enrolling only 13 participants, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Leon Berard

    Lyon, 69008, France

  • Institut Gustave Roussy

    Villejuif, 94805, France

Conditions

Explore the condition pages connected to this study.