METASTATIC GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Clinical trials for METASTATIC GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA explained in plain language.
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New drug combo aims to slow advanced esophageal cancer
Disease control OngoingThis study tested if adding an experimental drug called cixutumumab to standard chemotherapy (paclitaxel) could better control cancer that had spread or returned. It involved 94 adults with advanced esophageal or gastroesophageal junction cancer whose initial treatment had stoppe…
Matched conditions: METASTATIC GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 04, 2026 02:20 UTC
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Direct-Abdominal chemo tested for tough stomach cancers
Disease control OngoingThis early-stage study is testing whether delivering the chemotherapy drug paclitaxel directly into the abdominal cavity is safe and tolerable for people with advanced stomach or gastroesophageal cancer that has spread to the lining of the abdomen. The main goal is to find the hi…
Matched conditions: METASTATIC GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New drug duo tested for Tough-to-Treat esophageal cancer
Disease control OngoingThis early-stage study is testing the safety and effectiveness of combining two drugs, abemaciclib and ramucirumab, for people with advanced esophageal or gastroesophageal junction cancer that has spread. The trial is for patients whose cancer has continued to grow despite receiv…
Matched conditions: METASTATIC GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Scientists test new drug duo to fight tough cancers
Disease control OngoingThis early-stage study is testing a new combination of two drugs, sonidegib and pembrolizumab, for people with advanced solid tumors that have spread. The main goals are to find the safest dose of the combination and see if it helps shrink or control the cancer. The study is enro…
Matched conditions: METASTATIC GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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New drug combo targets Hard-to-Treat stomach cancers
Disease control OngoingThis study is testing whether adding an experimental drug called berzosertib to a standard chemotherapy drug (irinotecan) works better than the chemotherapy alone. It is for people with advanced stomach or esophageal junction cancer that has a specific genetic change (TP53 mutati…
Matched conditions: METASTATIC GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC