Metabolic dysfunction-associated steatotic liver disease
Clinical trials for Metabolic dysfunction-associated steatotic liver disease explained in plain language.
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Can exercise melt away liver fat?
Disease control By invitation onlyResearchers are testing whether aerobic exercise, resistance exercise, or a combination of both can reduce liver fat in adults with metabolic dysfunction-associated steatotic liver disease. The trial enrolls 186 people aged 18 to 45 with a body mass index between 25 and 40 and ev…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Could a gut bug help heal fatty liver? new trial begins
Disease control OngoingThis early-stage trial is testing whether a pasteurized gut bacterium called Akkermansia muciniphila can help people with metabolic dysfunction-associated steatotic liver disease (MASLD), a common fatty liver condition. About 40 adults will take either a low, medium, or high dose…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase 1 • Sponsor: Leeuwenhoek Laboratories Co. Ltd. • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Can a menopause-mimicking drug fight fatty liver in endometriosis patients?
Disease control OngoingThis study tests whether goserelin acetate, a drug that temporarily stops menstruation (like a short-term menopause), can reduce liver fat in women with endometriosis who also have fatty liver disease. Researchers will measure liver fat and stiffness using ultrasound in 62 women …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase 4 • Sponsor: Aristotle University Of Thessaloniki • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Could a diabetes drug turn back the biological clock in HIV?
Disease control By invitation onlyThis study investigates whether tirzepatide, a drug used for diabetes and weight loss, can reverse biological aging in people with HIV who are virally suppressed and have obesity. Participants receive tirzepatide for 25 weeks after a diet program. Researchers measure epigenetic a…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase 4 • Sponsor: National Taiwan University Clinical Trial Center • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Could a diabetes combo drug melt liver fat better than insulin alone?
Disease control OngoingThis study compares a combination diabetes drug (iGlarLixi) against insulin alone to see which better reduces liver fat in people with type 2 diabetes and a common fatty liver condition called MASLD. About 36 participants will take one of the two treatments for 12 weeks, and doct…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase 4 • Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Can a Step-by-Step program help latinos beat fatty liver?
Disease control OngoingThis study looks at whether a 26-week behavioral weight loss program called 'Paso a Paso' is practical for Mexican and Central American adults with fatty liver disease and overweight. Researchers will track attendance, weight loss, liver stiffness, and diet changes in 50 particip…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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AI spots silent liver danger in ER scans
Diagnosis By invitation onlyThis study tests a computer system that automatically finds fatty liver disease on emergency room scans and alerts doctors to tell patients and arrange follow-up care. About 4,700 adults with fatty liver seen on an ER scan will take part. The goal is to improve how often this hid…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Northwestern University • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC
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New MRI scan could replace painful liver biopsies for MASH patients
Diagnosis By invitation onlyThis study aims to see if a special MRI scan can accurately detect liver scarring (fibrosis) in people with a liver condition called MASH. Researchers will compare the MRI results with standard tests like ultrasound and blood work in 50 adults. If successful, this could offer a n…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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No needles, no pain: new ultrasound aims to spot fatty liver in kids fast
Diagnosis OngoingThis study checks if a quick ultrasound device called Velacur can accurately detect fatty liver disease (MASLD) in children aged 2 to 20. About 200 kids with suspected liver issues will get the ultrasound, and results will be compared to MRI or liver biopsy. The goal is to find a…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Emory University • Aim: Diagnosis
Last updated Jun 27, 2026 12:05 UTC
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Can a phone app help people with HIV beat fatty liver disease?
Symptom relief By invitation onlyThis study tests whether a mobile app-based nutritional program can help people living with HIV and fatty liver disease lose at least 5% of their body weight in 6 months. Participants are randomly assigned to use the app or receive standard lifestyle advice. The goal is to find a…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Hospital Universitari de Bellvitge • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Massive korean study maps the overlap of heart, kidney, and metabolic diseases
Knowledge-focused By invitation onlyThis study examines health data from about 800,000 Korean adults to see how often conditions like obesity, type 2 diabetes, heart disease, chronic kidney disease, and fatty liver occur together. Researchers will analyze national survey and insurance records from 2013 to 2023. No …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Simple blood test may spot hidden liver trouble in colitis patients
Knowledge-focused By invitation onlyThis study looks at whether two blood markers, zonulin and LBP, can help detect liver damage in people with both ulcerative colitis (UC) and fatty liver disease. Researchers will measure these markers and use a special ultrasound to check liver stiffness in 100 adults with UC who…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: University Hospital Dubrava • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Fatty liver linked to Body's own oxalate production in new study
Knowledge-focused OngoingThis study looks at how much oxalate the body naturally makes in people with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), a type of fatty liver. Researchers will collect urine samples from 28 adults after they eat a special low-oxalate diet. The goal is to be…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Major study aims to spare patients painful liver biopsies
Knowledge-focused By invitation onlyThis study follows 1,689 adults with fatty liver disease (MASLD) or MASLD with increased alcohol intake (MetALD) to see if non-invasive tests like MRI and Fibroscan can accurately track disease progression. The goal is to reduce the need for liver biopsies in future research and …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: HRI-MAIL-NIT • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC