MDS (MYELODYSPLASTIC SYNDROME)
Clinical trials for MDS (MYELODYSPLASTIC SYNDROME) explained in plain language.
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New hope for tough blood cancers: ARD103 trial opens
Disease control Recruiting nowThis study tests a new drug called ARD103 in adults whose acute myeloid leukemia or myelodysplastic syndrome has returned or not responded to standard treatments. The goal is to find a safe dose and see if the drug can shrink or control the cancer. About 49 participants will rece…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: PHASE1, PHASE2 • Sponsor: ARCE Therapeutics, Inc. • Aim: Disease control
Last updated May 26, 2026 05:14 UTC
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New cell addback aims to slash infection risk in child stem cell recipients
Disease control Recruiting nowThis study tests whether adding a specific type of immune cell (memory T cells) after a stem cell transplant can help prevent serious viral and fungal infections. About 100 children and young adults with blood cancers, immune disorders, or bone marrow failure will receive this ex…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated May 26, 2026 05:11 UTC
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New drug combo aims to free MDS patients from frequent blood transfusions
Disease control Recruiting nowThis study tests whether combining two drugs, luspatercept and darbepoetin alfa, can help people with a certain type of lower-risk myelodysplastic syndrome (MDS) need fewer blood transfusions. The trial enrolls 60 adults who currently rely on red blood cell transfusions. The goal…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated May 26, 2026 05:11 UTC
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New hope for tough blood cancers? early trial of CG009301 begins
Disease control Recruiting nowThis early-phase study tests a new drug called CG009301 in adults with blood cancers (like leukemia or MDS) that returned or didn't respond to standard treatments. The main goals are to find a safe dose and see if the drug can help control the disease. About 45 participants will …
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: PHASE1 • Sponsor: Cullgen (Shanghai),Inc • Aim: Disease control
Last updated May 26, 2026 05:09 UTC
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Double stem cell transplant shows promise for tough blood cancers
Disease control Recruiting nowThis study tests a new way to do stem cell transplants for people with acute myeloid leukemia (AML) or high-risk myelodysplastic syndromes (MDS). It combines stem cells from a half-matched donor (haploidentical) with cord blood, given at different times. The goal is to help the b…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: NA • Sponsor: Fujian Medical University Union Hospital • Aim: Disease control
Last updated May 26, 2026 05:06 UTC
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New drug cocktails aim to tame deadly transplant complication
Disease control Recruiting nowThis study is for people with blood cancers who need a stem cell transplant from an unrelated donor with a different blood type. The goal is to find which drug combination works best to prevent graft-versus-host disease (GVHD), a serious complication where donor cells attack the …
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: PHASE2 • Sponsor: Center for International Blood and Marrow Transplant Research • Aim: Disease control
Last updated May 26, 2026 05:05 UTC
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Weekly shot may speed platelet recovery after transplant in blood disorders
Disease control Recruiting nowThis study tests whether a once-weekly injection (romiplostim) can help platelets recover faster and more safely after a donor stem cell transplant in people with myelodysplastic syndrome (MDS) or severe aplastic anemia. About 66 adults will be randomly assigned to receive either…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated May 26, 2026 05:04 UTC
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Could bone marrow from deceased donors offer a new lifeline for blood cancer patients?
Disease control Recruiting nowThis early-phase study is testing whether bone marrow from deceased donors can be safely used for transplants in people with blood cancers like leukemia and lymphoma. About 12 patients will receive either strong or milder chemotherapy before the transplant. Researchers will monit…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: PHASE1, PHASE2 • Sponsor: Ossium Health, Inc. • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New drug aims to speed platelet recovery in blood cancer transplants
Disease control Recruiting nowThis study tests whether a drug called romiplostim N01 can help rebuild platelets faster after a stem cell transplant for blood cancers like leukemia. About 130 adults will receive either the drug or standard care. The goal is to see if the drug reduces bleeding risk and speeds r…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: PHASE1 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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New hope for older leukemia patients: safer transplant prep may boost survival
Disease control Recruiting nowThis study tests a new combination of drugs (cladribine, lisaftolax, and busulfan) given before a stem cell transplant in people aged 50 and older with relapsed or hard-to-treat acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). The goal is to make the transplant saf…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: NA • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Broccoli compound may boost recovery after cord blood transplant
Disease control Recruiting nowThis study tests whether a dietary supplement called sulforaphane (found in broccoli) can safely help blood cell recovery in adults receiving a cord blood transplant for blood cancers like leukemia or MDS. The cord blood used has been frozen for 10 years or more, which can damage…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: NA • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
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New stem cell method aims to cut transplant risks for blood disease patients
Disease control Recruiting nowThis study is testing a new way to do stem cell transplants for people with severe aplastic anemia or other bone marrow failure diseases. The goal is to reduce serious side effects, like graft-versus-host disease, by giving fewer donor white blood cells along with the stem cells.…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Phase: PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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Smartwatches could help doctors personalize blood transfusions for cancer patients
Knowledge-focused Recruiting nowThis study is for 80 adults with blood cancers like MDS or AML who are starting treatment. Participants wear a smartwatch and answer questionnaires to track their activity, symptoms, and quality of life. The goal is to help doctors better understand when patients need blood trans…
Matched conditions: MDS (MYELODYSPLASTIC SYNDROME)
Sponsor: University of Oxford • Aim: Knowledge-focused
Last updated May 26, 2026 05:14 UTC