MASH
Clinical trials for MASH explained in plain language.
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Could a simple stomach tuck reverse fatty liver disease?
Disease control Recruiting nowThis study tests whether a minimally invasive procedure called endoscopic sleeve gastroplasty (ESG), which reduces stomach size by about 70%, can help people with obesity and a serious liver condition called MASH. Participants will be randomly assigned to receive either ESG plus …
Matched conditions: MASH
Phase: NA • Sponsor: Pichamol Jirapinyo, MD, MPH • Aim: Disease control
Last updated May 26, 2026 05:51 UTC
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Could a common heart drug be the key to reversing fatty liver disease?
Disease control Recruiting nowThis study tests if a low dose of digoxin, a drug currently used for heart conditions, can help people with NASH (a severe type of fatty liver disease). About 144 adults with NASH and liver scarring will take oral digoxin for a period. The goal is to see if the drug can reverse t…
Matched conditions: MASH
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
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New study aims to predict liver disease in HIV patients
Knowledge-focused Recruiting nowThis study looks at 320 people with HIV to create tools that can predict who will develop fatty liver disease or liver scarring. Researchers will track changes in liver health over time using ultrasound and a special scan called Fibroscan. The goal is to catch liver problems earl…
Matched conditions: MASH
Sponsor: Shanghai Public Health Clinical Center • Aim: Knowledge-focused
Last updated May 26, 2026 06:07 UTC
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Researchers Double-Check lab methods for chronic disease studies
Knowledge-focused Recruiting nowThis study aims to make sure lab tests, equipment, and procedures used in research on obesity, diabetes, heart disease, and bone disorders are accurate and give consistent results. It will involve up to 100 healthy volunteers and people with these conditions, aged 18 to 100. The …
Matched conditions: MASH
Sponsor: Bettina Mittendorfer • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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New ultrasound technique could replace needle biopsy for liver scarring
Knowledge-focused Recruiting nowThis study aims to see if a special ultrasound done through an endoscope (EUS-SWE) can accurately measure liver scarring (fibrosis) in people with fatty liver disease. About 300 adults will get the new ultrasound, a standard liver biopsy, and a FibroScan. The goal is to find out …
Matched conditions: MASH
Sponsor: Olympus Corporation of the Americas • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC