MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Clinical trials for MALIGNANT PERIPHERAL NERVE SHEATH TUMORS explained in plain language.
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Could selinexor shrink tough childhood tumors?
Disease control Recruiting nowThis study tests a drug called selinexor in children and young adults whose Wilms tumor, rhabdoid tumor, or other solid tumors have come back or not responded to treatment. The goal is to see if the drug can shrink tumors. About 45 participants will take selinexor pills, and doct…
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 10:10 UTC
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New drug targets Hard-to-Treat cancers missing key gene
Disease control Recruiting nowThis early-stage trial tests an experimental drug called MRTX1719 in adults with advanced solid tumors that have a missing MTAP gene. The study aims to find a safe dose and see if the drug can shrink tumors or slow their growth. About 336 participants with cancers like mesothelio…
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Phase: PHASE1 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated May 26, 2026 10:08 UTC
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Engineered immune cells take on childhood cancers in new trial
Disease control Recruiting nowThis early-stage trial tests a personalized cell therapy for children and young adults (up to age 21) with solid tumors that have come back or not responded to standard treatment. Doctors take the patient's own immune cells, modify them to recognize a protein called B7-H3 on tumo…
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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Blood test could spot rare cancer in NF1 patients years earlier
Knowledge-focused Recruiting nowThis study looks at whether a blood test (liquid biopsy) can find a rare cancer called MPNST earlier than current methods in adults with Neurofibromatosis Type 1 (NF1). About 1,000 participants will give blood samples and complete surveys every six months for five years. The goal…
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Sponsor: David Miller • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC
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Global effort to unlock secrets of rare nerve cancer
Knowledge-focused Recruiting nowThis study creates a worldwide database for people with malignant peripheral nerve sheath tumors (MPNST), a rare cancer often linked to the genetic condition neurofibromatosis type 1 (NF1). Researchers will collect medical records, tumor samples, and imaging data from over 1,000 …
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 18, 2026 12:13 UTC