MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Clinical trials for MALIGNANT PERIPHERAL NERVE SHEATH TUMORS explained in plain language.
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Engineered immune cells take aim at childhood cancers
Disease control Recruiting nowThis early-stage trial tests a new immunotherapy for children and young adults up to age 21 with solid tumors that have come back or not responded to standard treatment. The therapy uses the patient's own immune cells, which are modified in a lab to recognize and attack a protein…
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Could a cancer drug that blocks a key protein help kids with relapsed wilms tumor?
Disease control Recruiting nowThis phase II trial is testing the drug selinexor in people with Wilms tumor, rhabdoid tumor, MPNST, or other solid tumors that have returned or not responded to treatment. Selinexor works by blocking a protein called XPO1, which is often overactive in these cancers. The study ai…
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New drug targets hard-to-treat cancers with missing MTAP gene
Disease control Recruiting nowThis early-stage trial tests an experimental drug called MRTX1719 in adults with advanced solid tumors that have a missing MTAP gene. The study aims to find a safe dose and see if the drug can shrink tumors or slow their growth. About 336 participants with cancers like mesothelio…
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Phase: PHASE1 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Global MPNST registry aims to unlock secrets of rare nerve cancer
Knowledge-focused Recruiting nowThis study is building a worldwide database of people with malignant peripheral nerve sheath tumors (MPNST), a rare cancer often linked to the genetic condition neurofibromatosis type 1. Researchers will collect medical records, tumor samples, and genetic data to find patterns th…
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Blood test could spot rare nerve tumors years earlier in NF1 patients
Knowledge-focused Recruiting nowThis study is testing whether a blood test (liquid biopsy) can detect a rare but serious nerve tumor called MPNST earlier than current methods in adults with Neurofibromatosis Type 1 (NF1). Researchers will compare the timing of tumor detection by the blood test versus standard i…
Matched conditions: MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
Sponsor: David Miller • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC