MALIGNANT NEOPLASM

This early-stage study tested a new drug called HMBD-002, alone or with another drug (pembrolizumab), in 48 adults with advanced solid tumors (like lung or breast cancer) that had stopped responding to standard treatments. The main goals were to check safety, find the best dose, …

This early-phase study tested the safety of a new drug called MK-4700, given alone or with another cancer drug (pembrolizumab), in 5 people with advanced solid tumors that had stopped responding to other treatments. The main goal was to find a safe dose and see how the body handl…

This study tested a short-term talk therapy (psychodynamic psychotherapy) for 24 adults with advanced solid tumors and high emotional distress. The goal was to see if the therapy is safe, acceptable, and feasible. Researchers measured side effects, drop-out rates, and how well th…

This study looked at whether ringing a bell on the last day of radiation therapy helps cancer patients remember less distress from their treatment. 82 patients were split into two groups: one rang a bell, the other did not. Researchers then compared how each group remembered thei…

This study looked at whether one radiation treatment works as well as two for reducing pain from cancer that has spread to the bones. 102 adults with bone metastases and pain were randomly assigned to receive either a single dose or two doses of radiation. The main goal was to se…

This study tested whether using virtual reality (VR) for 15–30 minutes during a single chemotherapy session could help lower distress, anxiety, depression, and pain. 68 adults with any type of cancer and high distress levels took part. Half used VR with relaxing backgrounds, whil…

This study tested a team-based care program for 516 people with stage III or IV cancer. The program aimed to help them stay mobile, reduce pain, and improve quality of life. Researchers found that the program helped maintain physical function and eased pain over six months.

This study tested whether taking extra dietary fiber (from psyllium husk capsules) during pelvic radiation therapy can reduce long-term gut inflammation and side effects in cancer patients. 354 adults with cancers of the pelvis (like rectal, prostate, or gynecological cancers) we…

This study tested whether ketoconazole, a drug usually used for fungal infections, can help reduce skin rashes caused by EGFR inhibitor cancer therapy. 58 participants with ongoing rash were randomly assigned to receive ketoconazole or a placebo. The main goal was to see if the d…

This study tested whether using at-home monitoring devices (like a wristband pedometer, scale, and blood pressure cuff) can help improve care for cancer patients after they leave the hospital following surgery. The goal was to see if patients could use the equipment and if the da…

This study looked at whether it's possible to regularly measure muscle mass and physical abilities in children (ages 8-21) with newly diagnosed cancer. Researchers used simple tests like walking and grip strength, along with special scans, to track changes during treatment. The g…