MALIGNANT NEOPLASM

This study is testing a two-part treatment for advanced cancer. Doctors take a patient's own white blood cells, genetically modify them to recognize a specific cancer protein (NY-ESO-1), and infuse them back. This is combined with a vaccine made from the same protein to boost the…

This early-stage trial aims to find safe doses and understand side effects of several drug combinations for patients with advanced cancers that haven't responded to standard treatments. The study involves 155 participants with various advanced or metastatic cancers and some rare …

This study is testing whether using virtual reality (VR) goggles during painful procedures can help reduce pain and anxiety for cancer patients. Hospitalized patients undergoing a bone marrow biopsy or spinal tap will be randomly assigned to either use VR during the procedure or …

This study is testing whether a self-administered meditation program can help reduce anxiety and depression in cancer patients who are experiencing distress. 35 participants were randomly assigned to either use a meditation app daily for two weeks or to a waitlist control group. …

This study is testing whether a non-invasive brain stimulation technique can reduce nerve pain caused by a common chemotherapy drug. Researchers are comparing real magnetic stimulation to a fake (placebo) treatment and standard care in 56 cancer patients. The goal is to see if st…

This study is testing whether a common steroid drug called dexamethasone can help control severe shortness of breath in cancer patients. About 135 participants with cancer and significant breathlessness were randomly assigned to receive either the drug or a placebo for two weeks.…

This study aims to understand how cancer treatment affects children's muscle mass, physical strength, and aging markers. Researchers will measure 28 children and teens (ages 8-21) at diagnosis, during treatment, and after treatment using simple tests like walking and strength exe…

This study analyzes tumor samples from cancer patients who responded exceptionally well to treatments that typically don't work for most people with their disease. Researchers examine the genetic makeup of these tumors to understand what makes some patients respond so dramaticall…

This study is testing a secure website designed to help families with a known inherited cancer risk. The program helps the person who had genetic testing share their results and relevant health history with their at-risk relatives. The goal is to improve communication within fami…