MALIGNANT MELANOMA
Clinical trials for MALIGNANT MELANOMA explained in plain language.
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First patients test new pill targeting Cancer's genetic engine
Disease control TerminatedThis first-in-human study tested a new oral drug called IK-595 in adults with advanced solid tumors that have specific genetic changes (in RAS or RAF genes) and no other treatment options. The main goals were to find a safe dose, see how the body processes the drug, and check for…
Matched conditions: MALIGNANT MELANOMA
Phase: PHASE1 • Sponsor: Ikena Oncology • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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First human test for new brain cancer drug halted
Disease control TerminatedThis was a first-in-human study to test the safety and early signs of effectiveness of a new drug, PF-07284890, for people with advanced solid tumors that have a specific genetic change called a BRAF V600 mutation. The trial enrolled 65 participants with cancers like melanoma, lu…
Matched conditions: MALIGNANT MELANOMA
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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First human test of Pfizer's new cancer drug begins
Disease control TerminatedThis early-stage study tested the safety and determined the right dosage of a new drug called PF-08046031 for adults with advanced melanoma and other solid tumors that have spread and have no other approved treatment options. The main goal was to identify side effects and see how…
Matched conditions: MALIGNANT MELANOMA
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Early-Stage trial halted for advanced skin cancer treatment
Disease control TerminatedThis early-stage study tested a new two-drug combination (SAR444245 with cemiplimab) for people with advanced melanoma or squamous cell skin cancer that had spread and could not be removed by surgery. The main goal was to see if the combination could shrink tumors and determine a…
Matched conditions: MALIGNANT MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: Sanofi • Aim: Disease control
Last updated Mar 23, 2026 15:28 UTC
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Experimental cancer drug trial halted early
Disease control TerminatedThis study tested an experimental drug called vobramitamab duocarmazine in people with advanced prostate cancer that had stopped responding to hormone therapy, as well as other solid tumors. The trial aimed to see if the drug could slow cancer growth and shrink tumors. The study …
Matched conditions: MALIGNANT MELANOMA
Phase: PHASE2 • Sponsor: MacroGenics • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC