Malignant glioma
Clinical trials for Malignant glioma explained in plain language.
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Can a RAGE inhibitor tame brain swelling after tumor surgery?
Disease control Not yet recruitingThis phase 1 trial tests whether FPS-ZM1, a drug that blocks an inflammation pathway, can safely control brain swelling that often occurs after surgery for glioblastoma, a type of brain cancer. Researchers will give FPS-ZM1 with or without the steroid dexamethasone to about 24 ad…
Matched conditions: MALIGNANT GLIOMA
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Spinal fluid DNA test could personalize brain cancer therapy
Diagnosis Not yet recruitingThis study explores whether analyzing tumor DNA in cerebrospinal fluid can help doctors make better treatment decisions for people with malignant brain tumors or brain metastases from lung or breast cancer. Participants undergo a standard spinal tap or fluid collection, and the f…
Matched conditions: MALIGNANT GLIOMA
Sponsor: Alireza Mansouri • Aim: Diagnosis
Last updated Jul 10, 2026 00:00 UTC
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Can new PET scans guide brain tumor catheters more precisely?
Knowledge-focused Not yet recruitingThis study tests whether combining PET scans with two investigational tracers, [18F]FET and [18F]FMISO, along with MRI, can help doctors place catheters more accurately for delivering therapy to recurrent brain tumors (malignant gliomas). About 20 adults already enrolled in a mai…
Matched conditions: MALIGNANT GLIOMA
Early phase 1 • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Brain Tumor's hidden electrical signals could reveal its weaknesses
Knowledge-focused Not yet recruitingThis study will test whether a special brain scan called magnetoencephalography (MEG) can detect electrical differences within gliomas, the most common malignant brain tumors in adults. Researchers will scan 60 newly diagnosed patients before surgery to see if MEG can identify mo…
Matched conditions: MALIGNANT GLIOMA
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC