MAJOR DEPRESSIVE EPISODE

This study tested a text messaging program designed to reduce the risk of major depression in pregnant and postpartum individuals. 40 participants who were at risk but not currently depressed received tailored texts with links to helpful content and a peer chat feature. The goal …

This study tested two ways of giving electroconvulsive therapy (ECT) to 156 people with severe depression. One method uses a frontoparietal placement and the other a temporoparietal placement. The goal was to see which works better for depression while causing fewer memory side e…

This study looked at whether certain proteins, called beta-arrestins, can help predict how well people with major depression will respond to the antidepressant venlafaxine. Researchers measured these proteins in blood samples from 67 depressed patients and 20 healthy volunteers o…

This study followed 14 people who called a crisis hotline after terrorist attacks in Paris, London, Barcelona, and Strasbourg. Researchers wanted to see how their psychiatric symptoms, like post-traumatic stress disorder and major depression, changed over time. The goal was to le…

This study looked at 30 people—some with major depression and some without—to see if certain genes are turned on or off differently. Researchers checked blood samples over time to track how these gene changes might relate to the course of depression. The goal was to better unders…