LOCALLY ADVANCED RECTAL CANCER
Clinical trials for LOCALLY ADVANCED RECTAL CANCER explained in plain language.
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New study aims to find best Pre-Surgery treatment for older rectal cancer patients
Disease control Recruiting nowThis study compares two standard treatment approaches given before surgery for older adults (70+) with locally advanced rectal cancer. The goal is to see which approach helps people live longer and with fewer side effects. About 230 participants will be randomly assigned to one o…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: NA • Sponsor: Jules Bordet Institute • Aim: Disease control
Last updated May 26, 2026 05:14 UTC
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New combo therapy aims to shrink rectal tumors without surgery
Disease control Recruiting nowThis study tests whether adding radiotherapy to a combination of chemotherapy (CAPOX) and an immunotherapy drug (Toripalimab) can improve outcomes for people with locally advanced rectal cancer that is microsatellite stable. About 192 participants will receive either the drug com…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE2 • Sponsor: Fudan University • Aim: Disease control
Last updated May 26, 2026 05:13 UTC
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Could chemo and High-Dose radiation spare rectal cancer patients from surgery?
Disease control Recruiting nowThis study is testing whether giving chemotherapy first, followed by a higher dose of targeted radiation, can completely eliminate cancer in people with locally advanced rectal cancer. The goal is to see if this approach is safe and effective enough to avoid the need for surgery.…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE1 • Sponsor: University of Miami • Aim: Disease control
Last updated May 26, 2026 05:12 UTC
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New combo therapy aims to save rectums from surgery
Disease control Recruiting nowThis study tests whether adding the immunotherapy drug camrelizumab to standard chemoradiation can make rectal cancer disappear completely in more patients. About 44 adults with locally advanced rectal cancer will receive the combination before any surgery. The goal is to increas…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE2 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New combo therapy aims to boost complete response in rectal cancer
Disease control Recruiting nowThis study tests two different treatment plans for people with locally advanced rectal cancer that has not spread. One plan uses longer radiation followed by chemotherapy, while the other uses shorter radiation plus chemotherapy, an immunotherapy drug, and a painkiller that may h…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE2 • Sponsor: Fudan University • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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New hope for rectal cancer: combo therapy aims to avoid surgery
Disease control Recruiting nowThis study tests a mix of chemotherapy (CAPOX), an immunotherapy drug (Sintilimab), and short-course radiation that avoids healthy lymph nodes. It is for people with a specific type of advanced rectal cancer (MSS) who want to keep their anus. The goal is to see if the cancer disa…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: PHASE2 • Sponsor: Jinhua Central Hospital • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Could a nutrition drink ease cancer treatment side effects?
Symptom relief Recruiting nowThis study is testing a special nutrition supplement in 52 people with head and neck, lung, or rectal cancer who are receiving standard cancer treatments like chemotherapy or radiation. The goal is to see if the supplement can reduce serious side effects and help patients stay on…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Phase: NA • Sponsor: Fondazione del Piemonte per l'Oncologia • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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Cancer nutrition study aims to boost treatment success
Knowledge-focused Recruiting nowThis study follows 110 adults with head/neck, lung, or rectal cancer to track changes in their nutrition and body composition during standard treatment. Researchers measure daily food intake, muscle mass, and strength over time. The goal is to gather data that will help design a …
Matched conditions: LOCALLY ADVANCED RECTAL CANCER
Sponsor: Fondazione del Piemonte per l'Oncologia • Aim: Knowledge-focused
Last updated May 26, 2026 05:11 UTC