LEPTOMENINGEAL DISEASE
Clinical trials for LEPTOMENINGEAL DISEASE explained in plain language.
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New hope for Brain-Spread breast cancer: High-Dose methotrexate trial opens
Disease control Recruiting nowThis study tests a high dose of the chemotherapy drug methotrexate given through a vein in people with breast cancer that has spread to the lining of the brain. The goal is to see if it helps them live longer. The trial is for adults with certain types of breast cancer and is cur…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated May 26, 2026 10:46 UTC
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New hope for advanced breast cancer patients with brain metastases: Triple-Drug trial launches
Disease control Recruiting nowThis study tests whether a combination of two oral drugs (tucatinib and capecitabine) plus a chemotherapy given directly into the spinal fluid (intrathecal trastuzumab) can help people with HER2-positive breast cancer that has spread to the lining of the brain and spinal cord. Ab…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE2 • Sponsor: UNICANCER • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New combo therapy aims to fight deadly breast cancer spread to the brain
Disease control Recruiting nowThis study tests if radiation therapy followed by two targeted drugs (trastuzumab and pertuzumab) given directly into the spinal fluid is safe and helps people with HER2+ breast cancer that has spread to the lining of the brain and spinal cord (leptomeningeal disease). About 39 p…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE1, PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New registry aims to unlock secrets of rare brain cancer spread
Knowledge-focused Recruiting nowThis study creates a database to track leptomeningeal disease, a rare condition where cancer spreads to the membranes around the brain and spinal cord. Researchers will collect information from 50 adults in Germany about treatments, side effects, and survival. The goal is to bett…
Matched conditions: LEPTOMENINGEAL DISEASE
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated May 26, 2026 10:48 UTC