New hope for breast cancer patients with brain spread: drug combo plus radiation tested in 30-person trial
NCT ID NCT06016387
First seen Jan 31, 2026 · Last updated May 01, 2026 · Updated 10 times
Summary
This study is for people with HER2-positive breast cancer that has spread to the lining of the brain or spinal cord (leptomeningeal disease). It tests whether giving radiation first, followed by a combination of three drugs (tucatinib, trastuzumab, and capecitabine), can help control the cancer and improve survival. About 30 participants will take part to see if this approach is safe and effective.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sunnybrook Health Sciences Centre
RECRUITINGToronto, Ontario, M4N 3M5, Canada
Contact
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
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The Ottawa Hospital
RECRUITINGOttawa, Ontario, Canada
Contact Email: •••••@•••••
Conditions
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