LEPTOMENINGEAL DISEASE
Clinical trials for LEPTOMENINGEAL DISEASE explained in plain language.
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New attack on breast Cancer's deadliest brain spread
Disease control Recruiting nowThis study tests whether high-dose methotrexate given through an IV can help patients with breast cancer that has spread to the membranes surrounding the brain and spinal cord. Researchers want to see if this treatment helps patients live longer than 12 weeks and measures how wel…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Brain-Invading breast cancer targeted with direct spinal fluid treatment
Disease control Recruiting nowThis study is testing whether radiation therapy followed by two targeted cancer drugs delivered directly into the spinal fluid is safe and can help people live longer. It's for patients with HER2-positive breast cancer that has spread to the lining of the brain and spinal cord. T…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE1, PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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First human trial: spinal fluid vaccine targets deadly breast cancer brain spread
Disease control Recruiting nowThis early-stage study is testing a personalized immune vaccine for breast cancer patients whose cancer has spread to the membranes surrounding the brain and spinal cord. Researchers will inject the vaccine directly into the spinal fluid to see if it's safe and to find the highes…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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New Triple-Threat attack on breast Cancer's most devastating spread
Disease control Recruiting nowThis study is testing a combination of three drugs to treat a serious complication where HER2-positive breast cancer spreads to the fluid-filled lining around the brain and spinal cord. It aims to see if this approach can help patients live longer and improve their neurological s…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE2 • Sponsor: UNICANCER • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC