LANGERHANS CELL HISTIOCYTOSIS (LCH)
Clinical trials for LANGERHANS CELL HISTIOCYTOSIS (LCH) explained in plain language.
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New hope for rare blood cancer: drug cocktail targets stubborn LCH
Disease control OngoingThis study tests a three-drug combination (selinexor, thalidomide, and dexamethasone) in 40 adults with a rare blood disorder called Langerhans cell histiocytosis (LCH) that has not responded to or has returned after prior treatment. The goal is to see if the regimen can control …
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS (LCH)
Phase: PHASE2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated May 26, 2026 10:08 UTC
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Old drug, new hope: lenalidomide takes on rare histiocyte disorders
Disease control OngoingThis study tests whether the chemotherapy drug lenalidomide can shrink or stop rare immune cell diseases called Langerhans cell histiocytosis, Erdheim-Chester disease, and histiocytic sarcoma. Twelve adults with active disease that needs treatment will receive lenalidomide and be…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS (LCH)
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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Scientists hunt for genetic clues in rare blood disorders
Knowledge-focused TerminatedThis study looks at the DNA of people with rare blood diseases like Castleman disease and histiocytosis. The goal is to find genetic changes that could be targeted with existing or new treatments. About 135 participants will provide samples for genetic testing. The study is curre…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS (LCH)
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC