Kidney transplant

This study looks at how well the HPV9 vaccine (Gardasil 9) works in people who have had a kidney transplant. Researchers will measure antibody levels in 30 transplant recipients over 24 months and compare them to published data from healthy individuals. The goal is to see if the …

Researchers compare two fluids used to preserve donor kidneys before transplant: a new solution called HCA-N and the standard HTK solution. The trial enrolls 250 first-time kidney transplant recipients aged 18 to 65. Doctors check how often kidneys need dialysis within the first …

This trial tests a comprehensive approach to improve kidney care and increase transplant rates. It combines provider training, digital dashboards, and a mobile health app to educate patients and help them find living donors. The study includes 5,000 adults with advanced chronic k…

This study tests whether adding terlipressin to standard care helps maintain stable blood pressure during kidney transplant surgery. Researchers will compare two groups of 150 adults: one receiving terlipressin plus dobutamine, the other dobutamine alone. The main goal is to see …

This study tests a drug called sparsentan for people who have protein in their urine after a kidney transplant due to IgA nephropathy or FSGS. About 20 adults will take the drug once daily for 36 weeks to see if it safely reduces protein levels and protects kidney function. The g…

This early-phase study tests whether a single infusion of special immune cells (regulatory dendritic cells) from the kidney donor can help the recipient's body accept the new kidney with fewer side effects. 14 first-time kidney transplant recipients will receive the cells one wee…

This study tests whether dapagliflozin, a drug usually used for diabetes, can improve kidney function in people who have received a kidney from a living donor. Fifty-four adult transplant recipients will take either dapagliflozin or standard care for 12 months. Researchers will m…

This study tests whether a 6-month exercise and personalized diet plan can help patients with obesity (BMI 40-44) lose weight so they can become active on the kidney transplant waiting list. Ten adults who are currently listed as 'inactive' due to their weight will follow a fitne…

This study looks at whether giving testosterone to men with low testosterone and kidney failure can help them recover better after a kidney transplant. About 50 men will receive testosterone before and after their transplant, and their safety and recovery will be compared to a si…

This study focuses on people from racial and ethnic minority groups who volunteer to donate a kidney but often stop the evaluation process before donation. Researchers are building a risk index to identify who is likely to drop out, then testing a six-month support program delive…

This study looks at how the natural bacteria in the body (the microbiome) interact with immunosuppressant drugs taken by kidney transplant recipients. Researchers will collect samples from the gut, mouth, nose, and urine to see if the microbiome influences how the body processes …

This study tests kidney transplant patients for genetic mutations that raise the risk of cancer and other diseases. Researchers want to see how common these mutations are and if testing helps guide better cancer screening. About 177 participants from Mayo Clinic are involved, all…

This study tracks 300,000 donated kidneys from 2010 to 2025 across many countries. Researchers want to see why some kidneys are discarded and how to use them better. The goal is to help more people get transplants and reduce organ waste.