IVF

This study tested a ready-to-use calcium ionophore medium (GM508 CultActive) on eggs from 68 IVF patients who had low fertilization rates, poor embryo quality, or were over 40. The medium was applied shortly after sperm injection to try to improve fertilization and embryo develop…

This completed Phase 4 trial tested whether an oral progesterone pill (Seidigestan) can replace daily injections of ganirelix (Astarté) for preventing early ovulation during IVF. The study enrolled 150 healthy egg donors aged 18-33. If the pill works as well as the injections, it…

This study looked at whether giving a higher dose of vaginal progesterone to women with low progesterone levels on the day of embryo transfer could improve the chance of an ongoing pregnancy. 87 women undergoing a single frozen embryo transfer in an artificial cycle took part. Th…

This study compared two hormone protocols for women with high ovarian response undergoing IVF. One used progesterone (dydrogesterone) and the other used a GnRH antagonist. The goal was to see which approach leads to more eggs retrieved and higher pregnancy rates. 200 women partic…

This study looked at whether losing weight before in vitro fertilization (IVF) helps overweight and obese women have a live birth. Researchers split 158 women into two groups: one followed a diet and exercise program for 3 months before starting IVF, while the other did not. The …

This study tested a high dose of a fertility drug called follitropin delta, mixed with another hormone (hCG), in 118 women undergoing IVF. The goal was to see if this combination could improve the number of good-quality embryos. The study was completed and focused on women aged 1…

This study followed 214 children born from either CAPA-IVM (a gentler egg maturation method) or conventional IVF to see if their development and behavior differed at age 5. Researchers used parent questionnaires to assess communication, motor skills, problem-solving, and emotiona…

This study looked at 300 women undergoing frozen embryo transfer as part of IVF treatment. Researchers measured progesterone levels in the blood to understand how the body processes the hormone. The goal was to find out if low progesterone on transfer day leads to higher failure …

This study looked at 87 people who had no eggs retrieved during their first IVF egg collection. Researchers gave a second ovulation trigger to see if eggs could then be collected. The goal was to count how many eggs were retrieved and measure the timing between the trigger and th…