New IVF medium may help those with low fertilization rates
NCT ID NCT05722067
First seen Mar 25, 2026 · Last updated Jun 23, 2026 · Updated 20 times
Summary
This study tested a ready-to-use calcium ionophore medium (GM508 CultActive) on eggs from 68 IVF patients who had low fertilization rates, poor embryo quality, or were over 40. The medium was applied shortly after sperm injection to try to improve fertilization and embryo development. The goal was to see if it could increase normal fertilization and high-quality blastocyst formation.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Chang Gung Memorial Hospital
Kaohsiung City, 123, Taiwan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
calcium ionophore (GM508 CultActive) medium
What this could lead to
If it works, this could help people with low fertilization rates or poor embryo quality have better success with IVF.
What could go wrong
This was a small, completed study with no phase designation, so results may not apply to all IVF patients. The treatment is a lab procedure, not a drug, and success depends on many factors.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.