INTERSTITIAL LUNG DISEASE

This study tests a drug called emapalumab in 5 adults with a rare, fast-worsening lung disease caused by MDA5 antibodies. The drug aims to calm an overactive immune system to improve breathing and reduce the need for extra oxygen. Participants must have worsening lung function an…

This study tests whether a combination of three drugs (prednisone, azithromycin, and hydroxychloroquine) can slow lung function decline in adults with interstitial lung disease caused by specific gene variants. About 30 participants will receive either the triple therapy or stand…

This early-stage study tests whether injecting stem cells from donated umbilical cords is safe for people with interstitial lung disease, a condition that scars the lungs and makes breathing hard. About 24 adults will receive the treatment to find the safest dose and check for an…

This study looks at the long-term safety of an inhaled medication called treprostinil palmitil inhalation powder (TPIP) for people with pulmonary hypertension caused by interstitial lung disease. About 344 adults who finished a previous study will take the drug and be monitored f…

This study tests a new type of PET scan that uses a special probe to find a protein called DDR2, which is linked to lung scarring in interstitial lung disease. The goal is to see if this scan can diagnose the disease earlier and more accurately than current methods. The study wil…

This study looks at whether portable oxygen therapy, adjusted to each person's needs, helps people with chronic lung diseases like ILD and COPD be more active and feel better in daily life. Twenty-four adults who only have low oxygen when walking or exercising will try two types …

This study tests a new device called MoblO2 that automatically adjusts oxygen levels for people with COPD or interstitial lung disease who need supplemental oxygen. Instead of constantly checking and adjusting their oxygen flow, users set a maximum level and the device keeps thei…

This study looks at whether a 16-week home exercise program can improve how well the heart and lungs work in people with pulmonary hypertension linked to interstitial lung disease. About 30 adults will follow a structured exercise plan at home, and researchers will measure change…

This study will test whether playing active video games as part of a pulmonary rehab program can improve breathing and exercise ability in 42 adults with mild-to-moderate interstitial lung disease. Participants will be split into two groups: one doing video game-based exercises a…