IMMUNOSUPPRESSION

This study is testing whether using two types of medications together works better than using just one to control Crohn's disease in children and teenagers. Researchers will compare how well the treatments reduce symptoms and gut inflammation over about a year. The goal is to fin…

This study aims to see if a special ultrasound scan (FibroScan) can help doctors safely reduce the amount of anti-rejection drugs people need to take after a liver transplant. Participants who are at least 2 years post-transplant and stable will have their drug doses carefully lo…

This study is testing whether checking a patient's genes before a kidney transplant can help doctors prescribe the correct starting dose of a crucial anti-rejection drug called tacrolimus. It will compare this genetic-guided approach to the current standard of care to see if it g…

This study is testing if taking all anti-rejection drugs once a day is as safe and effective as taking them twice a day for people who have received a liver transplant. The goal is to make the lifelong medication routine easier to follow, which could help patients stick to their …

This is the first-ever study to test transplanting a whole bladder from a deceased donor into a patient with end-stage bladder disease. The goal is to see if this robotic surgery is a feasible and better-tolerated alternative to current major surgeries that use a piece of bowel. …

This study aims to understand why some people who survive severe injuries later develop serious infections and long-term health problems. Researchers will collect blood and bone marrow samples from 255 adults with major trauma injuries and compare them to samples from people havi…

This study aims to understand how genetic immune system problems affect oral health, particularly gum disease. Researchers will compare people with immune disorders, those with severe gum disease, and healthy volunteers by collecting samples like saliva, plaque, and blood. The go…