IMMUNE SYSTEM DISEASES

This is a first-in-human study to test the safety of a new type of engineered immune cell therapy for adults with specific lymphomas that have returned or not responded to prior treatments. Researchers modify a patient's own T-cells to better recognize and attack cancer cells car…

This study is testing whether an immunotherapy treatment called PVX108 is safe and effective for reducing allergic reactions to peanuts in children and adolescents. Researchers are enrolling 90 participants aged 4-17 with confirmed peanut allergy to see if the treatment helps the…

This study is testing whether a transplant of healthy blood-forming stem cells from a donor can safely give people with serious T-cell immune disorders a new, working immune system. The goal is to control these often life-threatening conditions by replacing the faulty immune cell…

This early-stage study is testing the safety of a new type of personalized cell therapy for adults with B-cell lymphoma that has come back or not responded to other treatments. Doctors take a patient's own immune cells (T cells), modify them in a lab to better target cancer, and …

This was an early-stage study to test the safety and find the right dose of a new oral drug called HMPL-523 for adults with immune thrombocytopenia (ITP), a condition where the immune system attacks platelets, causing a risk of bleeding. The study was designed to enroll adults wh…

This is an early-stage study testing the safety of a new cell therapy for adults with multiple myeloma that has come back or stopped responding to standard treatments. Doctors take a patient's own immune cells (T-cells), modify them in a lab to better recognize and attack cancer …

This study is testing a new cell therapy for people whose Hodgkin's or Non-Hodgkin's lymphoma has come back or hasn't responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better target cancer cells, and then infuse them back into th…

This study is testing a new type of treatment for people whose acute lymphoblastic leukemia (ALL) has come back or hasn't responded to other therapies. Doctors take a patient's own immune cells (T cells), genetically modify them to better find and attack leukemia cells, and add a…

This study aims to build a database to help researchers understand the autoimmune-like side effects that can occur from powerful cancer immunotherapy drugs. It will collect health data and samples from 32 adult cancer patients receiving these treatments. The goal is to learn who …