IGG4 RELATED DISEASE
Clinical trials for IGG4 RELATED DISEASE explained in plain language.
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New drug shows promise for rare inflammatory disease
Disease control CompletedThis study tested the drug zanubrutinib in 10 people with IgG4-related disease, a condition that causes swelling in glands and other organs. The goal was to see if the drug could reduce gland size and inflammation over 24 weeks. Researchers measured changes using PET-MRI scans.
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2 • Sponsor: Matthew C. Baker • Aim: Disease control
Last updated Jun 23, 2026 11:57 UTC
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New drug combo shows promise for rare autoimmune disease
Disease control CompletedThis study tested a new drug called rilzabrutinib combined with steroids in 27 adults with active IgG4-related disease, a rare condition causing inflammation and organ damage. The goal was to see if the combination could prevent disease flares better than steroids alone. Particip…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2 • Sponsor: Principia Biopharma, a Sanofi Company • Aim: Disease control
Last updated Jun 18, 2026 11:53 UTC
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Scientists investigate immune cell role in rare IgG4 disease
Knowledge-focused CompletedThis study looked at a rare disease called IgG4-related disease, which causes swelling and scarring in organs. Researchers compared immune cells in the blood of 75 people: those with the disease, those with Sjogren syndrome, and healthy volunteers. The goal was to better understa…
Matched conditions: IGG4 RELATED DISEASE
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:00 UTC