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Scientists investigate immune cell role in rare IgG4 disease

NCT ID NCT02899039

First seen May 12, 2026 · Last updated Jun 21, 2026 · Updated 6 times

Summary

This study looked at a rare disease called IgG4-related disease, which causes swelling and scarring in organs. Researchers compared immune cells in the blood of 75 people: those with the disease, those with Sjogren syndrome, and healthy volunteers. The goal was to better understand how certain T cells might be involved in the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • APHM

    Marseille, 13, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could improve understanding of IgG4-related disease and point toward new ways to diagnose or monitor it.

What could go wrong

This is an observational study, not a treatment trial. It is small (75 participants) and may not lead to direct clinical benefits.

Conditions

The condition(s) this trial relates to.

Immunoglobulin G4-Related Disease immunoglobulin G4-related sclerosing disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.