IGG4 RELATED DISEASE
Clinical trials for IGG4 RELATED DISEASE explained in plain language.
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Could a weekly shot shrink swollen glands in IgG4 disease?
Disease control Recruiting nowThis early-phase study tests a drug called efgartigimod in 5 adults with IgG4-related disease, a condition causing swollen glands and organ damage. Participants receive weekly injections for 12 weeks to see if it reduces swelling in tear glands, saliva glands, or the pancreas. Th…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2 • Sponsor: Stanford University • Aim: Disease control
Last updated May 26, 2026 07:31 UTC
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New combo drug trial aims to tame rare inflammatory disease
Disease control Recruiting nowThis study tests whether adding lenalidomide to standard prednisone treatment can better control active IgG4-related disease (IgG4-RD), a rare condition causing swelling and damage in organs. About 198 adults with active disease will receive either a low or higher dose of lenalid…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated May 26, 2026 07:22 UTC
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Engineered immune cells target Hard-to-Treat IgG4 disease
Disease control Recruiting nowThis study tests a new treatment called anti-BCMA-CD19 CAR-T cells for adults with IgG4-related disease that hasn't improved with standard therapies. The treatment involves collecting a patient's own immune cells, modifying them to target the disease, and infusing them back. Rese…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated May 26, 2026 07:22 UTC
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Could a single pill tame three rare immune diseases?
Disease control Recruiting nowThis study tests a drug that blocks a key immune signal (JAK1) in people with Behçet's disease, myositis, or IgG4-related disease. The goal is to see if it can control disease activity and reduce the need for long-term steroids. About 60 adults will take the drug and be monitored…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2 • Sponsor: UMC Utrecht • Aim: Disease control
Last updated May 18, 2026 12:12 UTC
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Immune cell therapy targets rare inflammatory disease
Disease control Recruiting nowThis early-stage trial tests a new cell therapy called ACE1831 for people with IgG4-Related Disease, a rare condition causing inflammation in multiple organs. The therapy uses immune cells from healthy donors to potentially control the disease. About 30 adults with active flares …
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Acepodia Biotech, Inc. • Aim: Disease control
Last updated May 18, 2026 12:07 UTC
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New PET scan tracer could outshine current standard for inflammation diagnosis
Diagnosis Recruiting nowThis study compares a new imaging tracer, [18F]-AlF-FAPI-74, with the standard FDG tracer in PET/CT scans for people with hard-to-diagnose inflammatory conditions like fever of unknown origin, IgG4-related disease, and axial spondyloarthritis. Researchers aim to see if the new tr…
Matched conditions: IGG4 RELATED DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Diagnosis
Last updated May 26, 2026 07:28 UTC