IGG4-RELATED DISEASE
Clinical trials for IGG4-RELATED DISEASE explained in plain language.
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Could a single pill tame three rare immune diseases?
Disease control Recruiting nowThis study tests a drug that blocks a key immune signal (JAK1) in people with Behçet's disease, myositis, or IgG4-related disease. The goal is to see if it can control disease activity and reduce the need for long-term steroids. About 60 adults will take the drug and be monitored…
Matched conditions: IGG4-RELATED DISEASE
Phase: PHASE2 • Sponsor: UMC Utrecht • Aim: Disease control
Last updated May 17, 2026 02:04 UTC
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Immune cell therapy targets rare inflammatory disease
Disease control Recruiting nowThis early-stage trial tests a new cell therapy called ACE1831 for people with IgG4-Related Disease, a rare condition causing inflammation in multiple organs. The therapy uses immune cells from healthy donors to potentially control the disease. About 30 adults with active flares …
Matched conditions: IGG4-RELATED DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Acepodia Biotech, Inc. • Aim: Disease control
Last updated May 17, 2026 01:59 UTC
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Immune cell therapy shows promise for Hard-to-Treat IgG4 disease
Disease control Recruiting nowThis study tests a new treatment called anti-BCMA-CD19 CAR-T cells for adults with IgG4-related disease that hasn't improved with standard therapies. Participants will have their immune cells collected, receive a short course of chemotherapy, and then get an infusion of the modif…
Matched conditions: IGG4-RELATED DISEASE
Phase: PHASE2 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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Promising drug may shrink swollen glands in rare disease
Disease control Recruiting nowThis early-stage study tests if efgartigimod can reduce swelling in the tear glands, saliva glands, or pancreas of adults with IgG4-related disease. Participants receive weekly infusions for 12 weeks and have regular checkups. The goal is to see if the drug can control the diseas…
Matched conditions: IGG4-RELATED DISEASE
Phase: PHASE2 • Sponsor: Stanford University • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New combo therapy aims to tame rare inflammatory disease
Disease control Recruiting nowThis study tests whether adding lenalidomide to standard prednisone treatment can better control active IgG4-related disease (IgG4-RD), a rare condition causing swelling and damage in organs. About 198 adults with active disease will receive either 5mg or 10mg lenalidomide plus p…
Matched conditions: IGG4-RELATED DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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New PET scan tracer could outshine current gold standard for inflammation
Diagnosis Recruiting nowThis study compares a new imaging tracer, [18F]-AlF-FAPI-74, with the standard [18F]-FDG in PET/CT scans for diagnosing three inflammatory conditions: fever of unknown origin, IgG4-related disease, and axial spondyloarthritis. Researchers aim to see if the new tracer is as good o…
Matched conditions: IGG4-RELATED DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Diagnosis
Last updated May 05, 2026 11:55 UTC